Cumberland to highlight 2025 financial, international, portfolio and clinical progress
NASHVILLE, Tenn., March 3, 2026 /PRNewswire/ — Cumberland Pharmaceuticals Inc. (Nasdaq: CPIX), a specialty pharmaceutical company, announced today that its product portfolio of FDA-approved brands delivered combined net revenues of $13.7 million during the fourth quarter of 2025, a 31% increase over the prior year period. Net revenues for the full year 2025 were $44.5 million an 18% increase over the prior year period, achieving the company’s target of double digit revenue growth. Cumberland ended the year with $76.8 million in total assets, $52.3 million in liabilities and $24.9 million of shareholders’ equity. The net loss for 2025 was $2.9 million, which was an improvement of $3.6 million from the prior year. When noncash items are added back the Adjusted Earnings for the full year were $1.7 million, a $2.7 million improvement over the prior year. In addition, cashflow from operations was $4.9 million in 2025 representing a $5.5 million increase over 2024. “We are pleased with Cumberland’s strong financial performance in 2025, and the progress made across our commercial and development portfolio,” said A.J. Kazimi, CEO of Cumberland Pharmaceuticals. “We delivered solid revenue growth, expanded our international presence, strengthened our commercial platform with the addition of Talicia® and achieved important reimbursement and clinical milestones. These accomplishments reflect the strength of our strategy and position Cumberland for continued growth as we work together to provide unique products that improve the quality of patient care.” 2025 HIGHLIGHTS INCLUDE: International Expansion In February 2025, Cumberland announced that its Vibativ® product received approval from the regulatory authorities in China, the world’s second-largest pharmaceutical market. The announcement follows an agreement that provides SciClone Pharmaceuticals with the exclusive rights to register, promote and distribute the product to patients in the Chinese market. In September 2025, Cumberland announced the launch of Vibativ in Saudi Arabia. The product launch follows an agreement with Tabuk Pharmaceutical Manufacturing Company to introduce Vibativ into the Middle East. The arrangement provided Tabuk exclusive rights to distribute Vibativ in Saudi Arabia and Jordan, with the option to expand into other countries in the region. Tabuk has obtained the final approvals needed to commercialize Vibativ in Saudi Arabia. In October 2025, Cumberland’s ibuprofen injection product received regulatory approval in Mexico. The company previously announced its partnership with PiSA Farmaceutica, a well-established Mexican pharmaceutical firm. Under the agreement, PiSA is provided with the exclusive supply and distribution rights for the ibuprofen product in the Mexican market while Cumberland provides regulatory and manufacturing support. PiSA plans to introduce the product, making it accessible for a variety of clinical uses in Mexican healthcare facilities. Expanded Commercial Portfolio In October 2025, Cumberland announced arrangements with RedHill Biopharma Ltd. to jointly commercialize Talicia®, marking the latest addition to its commercial product portfolio. The FDA-approved oral capsule is indicated for the treatment of Helicobacter pylori (H. pylori) infection in adults, a bacterial infection and leading risk factor for gastric cancer. Through a co-commercialization agreement, Cumberland assumed responsibility for the distribution and sale of Talicia in the U.S. Cumberland records Talicia product sales and equally shares Talicia’s net revenues. Cumberland will provide an annual investment to cover certain distribution, marketing and sales costs. Leveraging its established field sales division, Cumberland leads the sales promotion for Talicia with the goal to increase the number of patients who benefit from the treatment. Talicia is the only all-in-one treatment containing omeprazole, amoxicillin and rifabutin, and is now recommended as a first-line therapy in the American College of Gastroenterology (ACG) clinical guidelines. Talicia is patent protected through 2042 and received eight years of U.S. market exclusivity under its Qualified Infectious Disease Product (QIDP) designation. CMS Establishes Reimbursement for Caldolor® Through Permanent J-Code Caldolor® received a key reimbursement milestone with the establishment of its permanent J-code, J1741, in December 2025. The J-Code is now officially linked to a CMS reimbursement price. This designation enables healthcare providers to access a clearly defined and reimbursable pathway for Caldolor, supporting its continued adoption across hospital and clinical settings. As the nation continues to address the opioid crisis, Caldolor offers an important non-opioid option for managing pain and fever. The availability of CMS reimbursement through J1741 enhances provider access to this therapy, supporting safer pain management strategies and helping reduce reliance on opioid medications. This reimbursement milestone reinforces Caldolor’s role as a clinically proven, non-opioid alternative and strengthens its position within hospital protocols and opioid-sparing treatment initiatives. It also supports broader access for patients while advancing efforts to improve outcomes and promote responsible pain management. Clinical Top-Line Study Results In early 2025, Cumberland announced positive top-line results from its FIGHT DMD clinical trial. The study evaluated ifetroban, a novel oral therapy for Duchenne muscular dystrophy (DMD) heart disease – the leading cause of death in DMD patients. It marks a breakthrough for these patients, as it is the first successful Phase II study specifically targeting the cardiac complications of their condition. Ifetroban has been studied in over 1,400 subjects across multiple clinical trials, demonstrating a well-established safety profile. The trial enrolled 41 DMD patients who received either low dose ifetroban (150 mg per day), high dose ifetroban (300 mg per day) or placebo. The study’s primary endpoint was an improvement in the heart’s left ventricular ejection fractions (LVEF). Key findings included:- High dose ifetroban treatment resulted in an overall 3.3% improvement in LVEF.
- The high dose ifetroban group showed an increase in 1.8% in LVEF, while the study placebo group showed an expected decline in LVEF of 1.5%.
- When compared with propensity matched natural history controls, the difference was even more pronounced, with the high dose treatment providing a significant 5.4% overall improvement in LVEF, as the control patients experienced a 3.6% decline in LVEF.
- Both doses of ifetroban were well-tolerated, with no serious drug-related events.
- Acetadote® (acetylcysteine) injection, for the treatment of acetaminophen poisoning;
- Caldolor® (ibuprofen) injection, for the treatment of pain and fever;
- Kristalose® (lactulose) oral, a prescription laxative, for the treatment of constipation;
- Sancuso® (granisetron) transdermal, for the prevention of nausea and vomiting in patients receiving certain types of chemotherapy treatment;
- Vaprisol® (conivaptan) injection, to raise serum sodium levels in hospitalized patients with euvolemic and hypervolemic hyponatremia;
- Vibativ® (telavancin) injection, for the treatment of certain serious bacterial infections including hospital-acquired and ventilator-associated bacterial pneumonia, as well as complicated skin and skin structure infections; and
- Talicia® (omeprazole, amoxicillin and rifabutin) oral capsule, for the treatment of H. pylori infection.
|
CUMBERLAND PHARMACEUTICALS INC. AND SUBSIDIARIES Consolidated Balance Sheets December 31, 2025 and 2024 (Unaudited) |
||||
|
2025 |
2024 |
|||
|
ASSETS |
||||
|
Current assets: |
||||
|
Cash and cash equivalents |
$ 11,444,693 |
$ 17,964,184 |
||
|
Accounts receivable, net |
16,944,780 |
11,701,466 |
||
|
Inventories, net |
6,225,518 |
3,999,995 |
||
|
Prepaid and other current assets |
2,445,276 |
2,786,513 |
||
|
Total current assets |
37,060,267 |
36,452,158 |
||
|
Non-current inventories |
9,253,090 |
11,005,499 |
||
|
Property and equipment, net |
264,724 |
277,365 |
||
|
Intangible assets, net |
14,027,921 |
17,973,449 |
||
|
Goodwill |
914,000 |
914,000 |
||
|
Operating lease right-of-use assets |
8,343,832 |
6,176,923 |
||
|
Investment in co-commercialization |
3,986,780 |
— |
||
|
Other assets |
2,973,378 |
2,784,016 |
||
|
Total assets |
$ 76,823,992 |
$ 75,583,410 |
||
|
LIABILITIES AND EQUITY |
||||
|
Current liabilities: |
||||
|
Accounts payable |
$ 18,567,546 |
$ 13,914,266 |
||
|
Operating lease current liabilities |
467,774 |
356,508 |
||
|
Revolving line of credit – current |
— |
5,100,000 |
||
|
Other investment liabilities |
5,074,504 |
— |
||
|
Other current liabilities |
12,635,095 |
12,250,955 |
||
|
Total current liabilities |
36,744,919 |
31,621,729 |
||
|
Revolving line of credit – long term |
5,240,733 |
10,176,170 |
||
|
Operating lease non-current liabilities |
4,471,965 |
4,939,739 |
||
|
Other long-term liabilities |
5,822,153 |
6,299,795 |
||
|
Total liabilities |
52,279,770 |
53,037,433 |
||
|
Commitments and contingencies |
||||
|
Equity: |
||||
|
Shareholders’ equity: |
||||
|
Common stock – no par value; 100,000,000 shares authorized; 14,956,627 |
51,684,381 |
46,821,425 |
||
|
Accumulated deficit |
(26,804,059) |
(23,967,931) |
||
|
Total shareholders’ equity |
24,880,322 |
22,853,494 |
||
|
Noncontrolling interests |
(336,100) |
(307,517) |
||
|
Total equity |
24,544,222 |
22,545,977 |
||
|
Total liabilities and equity |
$ 76,823,992 |
$ 75,583,410 |
||
|
CUMBERLAND PHARMACEUTICALS INC. AND SUBSIDIARIES Consolidated Statements of Operations (Unaudited) |
||||||||
|
Three months ended December 31, |
Years ended December 31, |
|||||||
|
2025 |
2024 |
2025 |
2024 |
|||||
|
Net revenues |
$ 13,678,651 |
$ 10,435,569 |
$ 44,521,431 |
$ 37,867,945 |
||||
|
Costs and expenses: |
||||||||
|
Cost of products sold |
2,241,344 |
1,976,473 |
6,667,207 |
6,585,972 |
||||
|
Selling and marketing |
6,208,695 |
4,222,554 |
19,098,153 |
17,023,023 |
||||
|
Research and development |
1,549,656 |
1,292,671 |
5,566,498 |
4,816,206 |
||||
|
General and administrative |
4,036,913 |
3,326,466 |
11,946,909 |
11,126,901 |
||||
|
Amortization and impairment |
1,013,245 |
1,459,444 |
4,034,657 |
4,748,252 |
||||
|
Total costs and expenses |
15,049,853 |
12,277,608 |
47,313,424 |
44,300,354 |
||||
|
Operating loss |
(1,371,202) |
(1,842,039) |
(2,791,993) |
(6,432,409) |
||||
|
Interest income |
91,967 |
106,667 |
476,748 |
334,444 |
||||
|
Equity in loss of investee |
(13,220) |
— |
(13,220) |
— |
||||
|
Other income – gain on insurance proceeds |
— |
— |
— |
237,089 |
||||
|
Interest expense |
(112,942) |
(223,261) |
(495,990) |
(605,508) |
||||
|
Loss before income taxes |
(1,405,397) |
(1,958,633) |
(2,824,455) |
(6,466,384) |
||||
|
Income tax benefit (expense) |
(23,245) |
56,996 |
(40,256) |
22,669 |
||||
|
Net loss |
(1,428,642) |
(1,901,637) |
(2,864,711) |
(6,443,715) |
||||
|
Net (income) loss at subsidiary attributable to |
16,950 |
(2,177) |
28,583 |
(36,055) |
||||
|
Net loss attributable to common shareholders |
$ (1,411,692) |
$ (1,903,814) |
$ (2,836,128) |
$ (6,479,770) |
||||
|
Loss per share attributable to common |
||||||||
|
Basic |
$ (0.09) |
$ (0.14) |
$ (0.19) |
$ (0.46) |
||||
|
Diluted |
(0.09) |
(0.14) |
(0.19) |
(0.46) |
||||
|
Weighted-average common shares outstanding: |
||||||||
|
Basic |
14,956,627 |
13,971,228 |
14,954,619 |
14,060,272 |
||||
|
Diluted |
14,956,627 |
13,971,228 |
14,954,619 |
14,060,272 |
||||
|
CUMBERLAND PHARMACEUTICALS INC. AND SUBSIDIARIES Condensed Consolidated Statements of Cash Flows Years ended December 31, 2025 and 2024 (Unaudited) |
||||
|
2025 |
2024 |
|||
|
Cash flows from operating activities: |
||||
|
Net loss |
$ (2,864,711) |
$ (6,443,715) |
||
|
Adjustments to reconcile net loss to net cash flows provided by (used |
||||
|
Depreciation and amortization expense |
4,145,201 |
4,902,560 |
||
|
Amortization of operating lease right-of-use asset |
1,140,738 |
1,140,738 |
||
|
Loss on co-commercialization investment |
13,220 |
— |
||
|
Disposal of assets |
— |
2,691 |
||
|
Stock-based compensation |
408,320 |
301,895 |
||
|
Increase (decrease) in non-cash contingent consideration |
46,569 |
(1,460,804) |
||
|
Increase in cash surrender value of life insurance policies over |
(142,927) |
(139,953) |
||
|
Noncash interest expense |
23,185 |
28,313 |
||
|
Life insurance proceeds |
— |
(237,089) |
||
|
Net changes in assets and liabilities affecting operating activities: |
||||
|
Accounts receivable |
(5,243,314) |
(1,943,290) |
||
|
Inventories, net |
2,242,616 |
2,408,397 |
||
|
Other current assets and other assets |
(231,829) |
189,112 |
||
|
Operating lease liabilities |
(836,100) |
1,784,089 |
||
|
Accounts payable and other current liabilities |
6,709,196 |
(991,359) |
||
|
Other long-term liabilities |
(477,642) |
(153,771) |
||
|
Net cash provided by (used in) operating activities |
4,932,522 |
(612,186) |
||
|
Cash flows from investing activities: |
||||
|
Additions to property and equipment |
(97,903) |
(66,461) |
||
|
Additions to intangible assets |
(84,402) |
(113,253) |
||
|
Net investment in manufacturing |
(2,477,192) |
— |
||
|
Other investment |
(2,000,000) |
— |
||
|
Increase in cash surrender value of life insurance policies |
(47,000) |
— |
||
|
Life insurance policy proceeds received |
— |
237,556 |
||
|
Net cash provided by (used in) investing activities |
(4,706,497) |
57,842 |
||
|
Cash flows from financing activities: |
||||
|
Borrowings on line of credit |
— |
38,488,920 |
||
|
Payments on line of credit |
(10,035,437) |
(35,996,894) |
||
|
Proceeds from ATM offering, net |
5,266,334 |
— |
||
|
Payments made in connection with repurchase of common shares |
(263,478) |
(579,049) |
||
|
Cash settlement of contingent consideration |
(1,712,935) |
(1,716,073) |
||
|
Net cash provided by (used in) financing activities |
(6,745,516) |
196,904 |
||
|
Net decrease in cash and cash equivalents |
(6,519,491) |
(357,440) |
||
|
Cash and cash equivalents, beginning of year |
17,964,184 |
18,321,624 |
||
|
Cash and cash equivalents, end of year |
$ 11,444,693 |
$ 17,964,184 |
||
|
CUMBERLAND PHARMACEUTICALS INC. AND SUBSIDIARIES Reconciliation of Net Income (Loss) Attributable to Common Shareholders to Adjusted Earnings (Loss) and (Unaudited) |
||||||||
|
Three months ended |
Three months ended |
|||||||
|
2025 |
2025 |
2024 |
2024 |
|||||
|
Earnings |
Earnings per |
Earnings |
Earnings per |
|||||
|
Net loss attributable to common shareholders |
$ (1,411,692) |
$ (0.09) |
$ (1,903,814) |
$ (0.14) |
||||
|
Less: Net loss (income) at subsidiary attributable to |
16,950 |
— |
(2,177) |
— |
||||
|
Net loss |
(1,428,642) |
(0.09) |
(1,901,637) |
(0.14) |
||||
|
Adjustments to net loss |
||||||||
|
Income tax benefit |
23,245 |
— |
(56,996) |
— |
||||
|
Depreciation and amortization |
1,041,895 |
0.07 |
1,496,394 |
0.11 |
||||
|
Share-based compensation (a) |
172,160 |
0.01 |
74,812 |
0.01 |
||||
|
Interest income |
(91,967) |
(0.01) |
(106,667) |
(0.01) |
||||
|
Interest expense |
112,942 |
0.01 |
223,261 |
0.02 |
||||
|
Adjusted Earnings (loss) and Adjusted Diluted |
$ (170,367) |
$ (0.01) |
$ (270,833) |
$ (0.02) |
||||
|
Diluted weighted-average common shares outstanding: |
14,956,627 |
13,971,228 |
||||||
|
Additional Information: |
||||||||
|
Reduction in the carrying amount of right-of-use assets (b) |
$ 285,184 |
$ 0.02 |
$ 285,184 |
$ 0.02 |
||||
|
Year ended December 31, |
Year ended December 31, |
|||||||
|
2025 |
2025 |
2024 |
2024 |
|||||
|
Earnings |
Earnings per |
Earnings |
Earnings per |
|||||
|
Net loss attributable to common shareholders |
$ (2,836,128) |
$ (0.19) |
$ (6,479,770) |
$ (0.46) |
||||
|
Less: Net loss (income) at subsidiary attributable to |
28,583 |
— |
(36,055) |
— |
||||
|
Net loss |
(2,864,711) |
(0.19) |
(6,443,715) |
(0.46) |
||||
|
Adjustments to net loss |
||||||||
|
Income tax (benefit) expense |
40,256 |
— |
(22,669) |
$ — |
||||
|
Depreciation and amortization |
4,145,201 |
0.27 |
4,902,560 |
$ 0.35 |
||||
|
Share-based compensation (a) |
408,320 |
0.03 |
301,895 |
$ 0.02 |
||||
|
Interest income |
(476,748) |
(0.03) |
(334,444) |
$ (0.02) |
||||
|
Interest expense |
495,990 |
0.03 |
605,508 |
$ 0.04 |
||||
|
Adjusted Earnings (loss) and Adjusted Diluted |
$ 1,748,308 |
$ 0.11 |
$ (990,865) |
$ (0.07) |
||||
|
Diluted weighted-average common shares outstanding: |
15,245,309 |
14,060,272 |
||||||
|
Additional Information: |
||||||||
|
Reduction in the carrying amount of right-of-use assets (b) |
$ 1,140,738 |
$ 0.07 |
$ 1,140,738 |
$ 0.08 |
||||
- Adjusted Earnings: Net income (loss) adjusted for the impact of income taxes, depreciation and amortization expense, share-based compensation, interest income and interest expense.
(a) Represents the share-based compensation of Cumberland.
(b) Represents the straight line reduction in carrying value of right-of-use assets.
- Adjusted Diluted Earnings Per Share: Adjusted loss divided by diluted weighted-average common shares outstanding.

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