- Revenue: US$959.5 million, +61.4% year-on-year
- Gross profit: US$553.2 million, +103.3% year-on-year
- Adjusted net profit: US$230.3 million, +285.0% year-on-year
- GenScript Life Science Group (LSG): US$522.1 million, +14.8% year-on-year
- ProBio: US$388.7 million, +309.1% year-on-year
- Bestzyme: US$58.0 million, +7.9% year-on-year
The Group continued to capture greater value from integration across its technology platforms. LSG’s gene-to-protein workflow became an increasingly important growth engine, with platform synergies contributing approximately 65% of LSG’s 2025 revenue growth. 2. Global reach and diversified revenue base
GenScript further strengthened its international footprint, growing across NA, EU, and APAC. Europe delivered five consecutive years of growth, with 2025 revenue increasing 29% year-on-year, while Asia-Pacific grew 33% year-on-year, underscoring broader geographic diversification. 3. Product and technology innovation
GenScript continued to advance proprietary technologies and product platforms spanning life science research tools, biologics discovery and development, and industrial biotechnology applications. These innovations strengthened differentiation, improved productivity, and supported customer adoption across high-growth applications. 4. Automation and digitalization
Expanded use of automation and AI-enabled systems in R&D and manufacturing, improved efficiency, shortened timelines, and enhanced operational resilience. Within 2025, four major production sites of LSG are upgraded into automated, AI-driven “lights-out” facilities, and 60% of global production capacity will be powered by AI-driven automation by end-2026. Business Segment Highlights GenScript Life Science Group
GenScript LSG generated US$522.1 million in revenue, up 14.8% year-on-year, surpassing the US$500 million milestone. The business continued to benefit from adoption of its integrated gene-to-protein platform, strong demand from pharma and biotech customers, and growing traction in AI-enabled discovery. Among key highlights:
- Revenue from integrated protein expression services grew +50%.
- Orders flowing from gene synthesis into integrated protein expression platform increased +160% year-on-year.
- Serving 66,000+ active customers globally and cited in 118,000+ publications, reinforcing its position as a trusted, global scientific community partner.
ProBio delivered exceptional growth in 2025, with revenue reaching US$388.7 million, up 309.1% year-on-year. Excluding one-time items, fee-for-service revenue grew 21% year-on-year, with improving order momentum. ProBio secured 41 antibody & protein drug development projects; 60 cell and gene therapy CDMO projects and 20 new IND clearances across CGT programs. Expanding its discovery, CMC, and GMP manufacturing capabilities, ProBio strengthened its position with international customers and advanced flexible collaboration models – including fee-for-service, co-development, and out-licensing. Bestzyme
Bestzyme generated US$58.0 million revenue, up 7.9% year-on-year. The business continued advancing industrial biotechnology innovation through new enzyme products, stronger AI-enabled R&D capabilities, and international market development. Performance highlights include increased contribution from innovative enzyme products, progress in sweet protein commercialization, and 140% improvement in R&D efficiency driven by AI-powered workflows. A Resilient Global Operating Network: Automation, Worldwide Operations, ESG
GenScript continued to reinforce its global operating network to support long-term, high-quality growth. In 2025, the Group advanced its manufacturing footprint across NA, EU, and APAC, with increasing use of automation and digitalization to improve productivity, speed, and reliability. GenScript’s global operating model is designed to support stronger service consistency, greater supply resilience, and scalable execution across its businesses. ESG Leadership and Responsible Growth
GenScript strengthened its ESG profile, being recognized by leading external benchmarks:
- MSCI ESG Rating upgraded to AA
- Included in the FTSE4Good Index Series
- Awarded EcoVadis Silver Medal
- Included in the S&P Sustainability Yearbook
- strengthening cross-platform synergy
- broadening global customer reach
- improving leverage through automation and digitalization
- advancing proprietary technologies across biologics and industrial biotechnology
- 15%–18% revenue growth for GenScript LSG
- 20%–25% fee-for-service revenue growth for ProBio
- 10%–15% revenue growth for Bestzyme
Media Inquiries: [email protected]
Company Website: https://www.genscript.com
|
FINANCIAL REVIEW |
|||||
|
2025 |
2024 |
Change |
|||
|
US$’000 |
US$’000 |
US$’000 |
|||
|
Continuing operations |
|||||
|
Revenue |
959,526 |
594,486 |
365,040 |
||
|
Gross profit |
553,204 |
272,125 |
281,079 |
||
|
Loss after income tax expense |
(532,404) |
(173,774) |
(358,630) |
||
|
Adjusted net profit |
230,345 |
59,826 |
170,519 |
||
|
Discontinued operation |
|||||
|
Loss for the period from Legend Group, net of tax |
– |
(203,149) |
203,149 |
||
|
Gain on deconsolidation of Legend Group, net of tax |
– |
3,232,210 |
(3,232,210) |
||
|
(Loss)/Profit for the year |
(532,404) |
2,855,287 |
(3,387,691) |
||
|
(Loss)/Profit attributable to owners of the Company |
(532,830) |
2,961,877 |
(3,494,707) |
||
|
(Loss)/Earnings per share for the year (US cent) |
|||||
|
-Basic |
(24.58) |
139.63 |
(164.21) |
||
|
-Diluted |
(24.58) |
135.97 |
(160.55) |
||
|
Adjusted profit and expenses: |
|||||
|
Gross profit |
556,576 |
280,320 |
276,256 |
||
|
Selling and distribution expenses |
95,963 |
83,731 |
12,232 |
||
|
Administrative expenses |
122,668 |
106,883 |
15,785 |
||
|
R&D expenses |
69,237 |
52,123 |
17,114 |
(i) share-based compensation expenses;
(ii) the impact of acquisitions and fair value losses on preferred shares;
(iii) losses from foreign exchange forward and option contracts;
(iv) impairment losses on long-term assets;
(v) foreign exchange gains or losses;
(vi) fair value gains or losses on non-current financial assets;
(vii) unrealized financing costs related to equity financing activities;
(viii) share of losses from Legend Biotech and service fees related to deconsolidation; and
(ix) impairment of investments in Legend Biotech. This document is intended to provide a summary overview and does not constitute a complete description of the Company, its securities, or related matters. For more detailed information, please refer to the official announcement released by GenScript Group on March 15 on the Company’s website. All information is subject to the official announcement. Photo – https://mma.prnewswire.com/media/2934501/GS_2025_Annual_Results_GenScript.jpg
Logo – https://mma.prnewswire.com/media/2855189/GenScript_Logo.jpg

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