MANASSAS, Va., Feb. 28, 2026 /PRNewswire/ — PureHealth Research has launched its Natural GLP-1 Support collection, a line of natural GLP-1 supplements offering a needle-free, prescription-free alternative to synthetic injections that can cost thousands of dollars per year. The collection is led by GLP ON, a physician-approved 9-ingredient formula that targets the entire GLP-1 system at clinically studied dosages.
How These Natural GLP-1 Supplements Work Across Three Pathways
Where most competing formulas rely on a single ingredient like berberine alone, GLP ON addresses three distinct phases of GLP-1 activity. Berberine activates the AMPK enzyme for glucose metabolism support while working alongside African Mango to slow GLP-1 degradation. Chlorogenic acids in Green Coffee Extract, the patented citrus flavonoid Eriomin®, and Akkermansia Muciniphila promote GLP-1 secretion from intestinal L-cells. Vitamin D3 supports GLP-1 sensitivity, a mechanism rarely addressed by competitors.
This approach is rooted in gut microbiome science. Beneficial bacteria ferment prebiotic fibers into short-chain fatty acids like butyrate, which directly stimulate L-cells to release GLP-1. Every ingredient is backed by peer-reviewed research and included at effective clinical dosages, setting the collection apart from products that rely on sub-clinical amounts.
The Best Natural GLP-1 Supplements for Long-Term Use
The collection also includes CurbFit, GLP Digest+, GLP Fusion, Blood Sugar Formula, and Berberine Extract, each targeting complementary aspects of metabolic wellness. All products are manufactured in the USA, third-party tested, and designed to be safe for long-term daily use.
Key differentiators across the collection:
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+1 (888) 558-9836 (Toll-Free, US)
+1 (863) 301-4007 (International)
10199 Dean Drive, Manassas, VA 20110, USA. Logo – https://mma.prnewswire.com/media/2902972/5823145/PureHealth_Research_Logo.jpg SOURCE PureHealth Research LLC
- Clinically studied dosages backed by peer-reviewed research
- Needle-free oral supplementation at a fraction of injectable costs
- No prescription required and safe for long-term daily use
- Suitable for individuals transitioning off injectable programs
- Physician-approved and manufactured in the USA
[email protected]
+1 (888) 558-9836 (Toll-Free, US)
+1 (863) 301-4007 (International)
10199 Dean Drive, Manassas, VA 20110, USA. Logo – https://mma.prnewswire.com/media/2902972/5823145/PureHealth_Research_Logo.jpg SOURCE PureHealth Research LLC

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